3,4-DIMETHOXYBENZYL BROMIDE

3,4-DIMETHOXYBENZYL BROMIDE - Names and Identifiers

Name	4-(bromomethyl)-1,2-dimethoxybenzene
Synonyms	Veratryl bromide 3,4-DIMETHOXYBENZYL BROMIDE Toluene, α-bromo-3,4-dimethoxy- 4-(bromomethyl)-1,2-dimethoxybenzene 4-(BroMoMethyl)-1,2-diMethoxybenzene Benzene, 4-(broMoMethyl)-1,2-diMethoxy- 3,4-DiMethoxybenzyl BroMideDiscontinued due to stability
CAS	21852-32-4
InChI	InChI=1/C9H11BrO2/c1-11-8-4-3-7(6-10)5-9(8)12-2/h3-5H,6H2,1-2H3

3,4-DIMETHOXYBENZYL BROMIDE - Physico-chemical Properties

Molecular Formula	C9H11BrO2
Molar Mass	231.09
Density	1.384
Melting Point	56-58℃
Boling Point	273℃
Flash Point	116℃
Solubility	CDCl3;
Vapor Presure	0.00991mmHg at 25°C
Appearance	Solid
Color	Off-white
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.538

3,4-DIMETHOXYBENZYL BROMIDE - Introduction

4-(bromomethyl)-1,2-dimethoxybenzene is an organic compound with the chemical formula C9H11BrO2. The following is a description of its nature, use, preparation and safety information:

Nature:
4-(bromomethyl)-1,2-dimethoxybenzene is a colorless to light yellow solid with a special aromatic odor. It is soluble in organic solvents such as chloroform, dichloromethane and ethanol at room temperature, but hardly soluble in water. It has a high melting and boiling point.

Use:
4-(bromomethyl)-1,2-dimethoxybenzene is mainly used as an intermediate in organic synthesis. It is often used in the preparation of other organic molecules, such as bromine-containing compounds, ethers and dialkyl, as well as in the synthesis of certain drugs and pesticides. Because of its aromatic structure and chemical reactivity, it also has certain application value in the field of pharmaceutical research and pharmaceutical chemistry.

Method:
4-(bromomethyl)-1,2-dimethoxybenzene can generally be prepared by esterification of benzene and 2,3-dimethoxybenzyl alcohol under alkali catalysis. A base catalyst such as sodium hydride or Potassium hydride in the reaction can promote ester bond formation. During the preparation process, attention should be paid to the control of reaction conditions, such as temperature, reaction time and molar ratio of reactants.

Safety Information:
4-(bromomethyl)-1,2-dimethoxybenzene is relatively safe under normal use conditions, but appropriate protective measures still need to be taken. It may be irritating and corrosive to the eyes, skin and respiratory system, so appropriate personal protective equipment such as laboratory gloves, goggles and protective face masks should be worn during operation. At the same time, it should be operated in a well-ventilated place to avoid inhaling its volatile products. During storage and handling, contact with oxidizing agents and strong acids should be avoided to avoid dangerous reactions. In the event of an accident or maladjustment, medical help should be sought immediately.

Last Update：2024-04-09 21:11:58